Giulio G Muccioli Selected Research

glyceryl 2-arachidonate (2-arachidonoylglycerol)

1/2019	The α/β-hydrolase domain 6 inhibitor WWL70 decreases endotoxin-induced lung inflammation in mice, potential contribution of 2-arachidonoylglycerol, and lysoglycerophospholipids.
4/2012	Inhibitors of the endocannabinoid-degrading enzymes, or how to increase endocannabinoid's activity by preventing their hydrolysis.
2/2012	Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth.
8/2011	Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation.
8/2010	The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors.
2/2008	An optimized GC-MS method detects nanomolar amounts of anandamide in mouse brain.

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Giulio G Muccioli Research Topics

Disease

41	Inflammation (Inflammations) 11/2022 - 08/2007
19	Obesity 01/2022 - 02/2006
18	Neoplasms (Cancer) 01/2022 - 01/2011
10	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2021 - 06/2011
10	Colitis 02/2019 - 08/2011
6	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2022 - 02/2006
6	Pain (Aches) 01/2021 - 03/2014
5	Neuroinflammatory Diseases 03/2018 - 01/2008
4	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2013
3	Cachexia 12/2021 - 01/2015
3	Carcinoma (Carcinomatosis) 12/2021 - 10/2016
3	Body Weight (Weight, Body) 12/2021 - 07/2011
3	Metabolic Diseases (Metabolic Disease) 01/2021 - 02/2011
3	Hyperalgesia 01/2021 - 11/2015
3	Neuroblastoma 06/2013 - 01/2011
2	Hyperlipidemias (Hyperlipidemia) 01/2022 - 01/2021
2	Myalgia 01/2022 - 04/2016
2	Pneumonia (Pneumonitis) 01/2021 - 01/2019
2	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2021 - 01/2020
2	Ulcerative Colitis 02/2019 - 04/2016
2	Insulin Resistance 01/2017 - 01/2011
2	Necrosis 04/2016 - 03/2012
2	Hypersensitivity (Allergy) 11/2015 - 08/2007
2	Glucose Intolerance 03/2015 - 01/2013
2	Leukemia 01/2015 - 01/2014
2	Pathologic Processes 04/2012 - 01/2006
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2022
1	Digestive System Diseases 12/2021
1	Malnutrition (Nutritional Deficiencies) 12/2021
1	Weight Loss (Weight Reduction) 12/2021
1	Asthma (Bronchial Asthma) 01/2021
1	Lung Diseases (Lung Disease) 01/2021
1	Hypobetalipoproteinemias (Hypobetalipoproteinemia) 01/2021

Drug/Important Bio-Agent (IBA)

26	LipidsIBA 09/2021 - 02/2008
18	EndocannabinoidsIBA 01/2021 - 08/2007
8	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2011
8	Pharmaceutical PreparationsIBA 10/2020 - 01/2006
7	OxysterolsIBA 11/2022 - 01/2016
7	N-acylethanolaminesIBA 01/2021 - 02/2008
6	LipopolysaccharidesIBA 01/2021 - 08/2011
6	EnzymesIBA 01/2021 - 01/2008
6	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 01/2019 - 02/2008
6	anandamide (arachidonylethanolamide)IBA 01/2018 - 02/2008
6	palmidrolIBA 01/2018 - 01/2011
6	Cannabinoid Receptors (Cannabinoid Receptor)IBA 11/2015 - 01/2006
4	Proteins (Proteins, Gene)FDA Link 12/2021 - 06/2009
4	ProstaglandinsIBA 01/2021 - 10/2013
4	Messenger RNA (mRNA)IBA 01/2021 - 01/2011
3	Lactic Acid (Lactate)FDA LinkGeneric 01/2022 - 04/2017
3	PrebioticsIBA 09/2021 - 11/2011
3	Inulin FDA Link 09/2021 - 08/2011
3	CytokinesIBA 01/2021 - 10/2013
3	CholesterolIBA 01/2021 - 01/2016
3	1-dodecylpyridoxal (PLD)IBA 01/2020 - 03/2015
3	EstersIBA 01/2019 - 10/2013
3	Dextran SulfateIBA 12/2018 - 10/2013
3	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2018 - 11/2011
3	LigandsIBA 01/2018 - 08/2011
2	GlucansIBA 01/2022 - 11/2020
2	ChitinIBA 01/2022 - 11/2020
2	Butyrates (Butyrate)IBA 01/2022 - 01/2015
2	Bile Acids and Salts (Bile Acids)IBA 12/2021 - 01/2021
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2021 - 01/2011
2	25-hydroxycholesterolIBA 01/2021 - 02/2019
2	AcidsIBA 01/2021 - 02/2015
2	amidaseIBA 01/2021 - 02/2015
2	CarrageenanIBA 01/2021 - 01/2019
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 04/2016
2	QuinonesIBA 02/2020 - 01/2020
2	EndotoxinsIBA 01/2019 - 06/2018
2	Prostaglandin D2IBA 01/2019 - 01/2018
2	Sulfonic AcidsIBA 12/2018 - 08/2011
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2018 - 01/2015
2	N-oleoylethanolamineIBA 01/2018 - 01/2011
2	Peroxidase (Myeloperoxidase)IBA 01/2018 - 04/2016
2	InterferonsIBA 09/2017 - 04/2016
2	Antineoplastic Agents (Antineoplastics)IBA 10/2016 - 04/2016
2	CannabinoidsIBA 11/2015 - 05/2011
2	CB2 Cannabinoid ReceptorIBA 02/2015 - 09/2013
2	CarbohydratesIBA 01/2015 - 08/2011
2	Monoacylglycerol LipasesIBA 10/2013 - 08/2011
1	Alanine (L-Alanine)FDA Link 01/2022
1	AdipokinesIBA 01/2022
1	Pyruvic Acid (Pyruvate)IBA 01/2022
1	Dietary Fiber FDA Link 01/2022
1	Atorvastatin (Lipitor)FDA Link 01/2022
1	Ursodeoxycholic Acid (Urso)FDA LinkGeneric 12/2021
1	Branched-Chain Amino AcidsIBA 12/2021
1	Serum AlbuminIBA 12/2021
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 12/2021
1	Leukocyte L1 Antigen Complex (Calgranulin)IBA 09/2021
1	Apolipoproteins E (ApoE)IBA 01/2021
1	ApolipoproteinsIBA 01/2021
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 01/2021
1	fatty-acid amide hydrolase (fatty acid amide hydrolase)IBA 01/2021
1	Protein Kinases (Protein Kinase)IBA 01/2021
1	cadherin 5IBA 01/2021

Therapy/Procedure

7	Therapeutics 01/2022 - 04/2016
2	Oral Administration 04/2016 - 02/2015
1	Traditional Medicine (Folk Remedies) 01/2022